2、荧光成像导航肿瘤手术切除；

 
    3、肿瘤微环境响应的多模式探针和靶向治疗。

 
    主持项目：

 
    1、谷胱甘肽响应的近红外二b区荧光探针用于荧光成像引导手术切除和光热治疗的研究，国家自然科学基金青年基金项目，主持，25万， 2020.1-2022.12，项目编号：61905248.

 
    近期代表性论文：

 
    1. P Wang, Y Fan, L Lu, L Liu, L Fan^*, M Zhao, Y Xie, C Xu, F Zhang^*, NIR-II nanoprobes in-vivo assembly to improve image-guided surgery for metastatic ovarian cancer, Nature Communications, 2018, 9: 2898;

 
    2. P Wang^#, X Li^#, C Yao, W Wang, M Zhao, A M El-Toni and F Zhang^*, Orthogonal near-infrared upconversion co-regulated site-specific O2 delivery and photodynamic therapy for hypoxia tumor by using red blood cell microcarriers, Biomaterials, 2017, 125: 90-100；

 
    3. P Wang^#, C Wang^#, L Lu, C Yao, X Li^*, W Wang, M Zhao, T Zhao, L Hu and F Zhang^*, Kinetics-mediate fabrication of multi-model bioimaging lanthanide nanoplates with controllable surface roughness for blood brain barrier transportation, Biomaterials, 2017, 141: 223-232；

 
    4. L Hu^#, P Wang^#, M Zhao, L Liu, L Zhou, B Li, F H A, A M El-Toni, X Li, Y Xie, X Sun, F Zhang, Near-Infrared Rechargeable “Optical Battery” Implant for Irradiation-Free Photodynamic Therapy, Biomaterials, 2018, 163: 154-162；

 
    5. P Wang, X Wang, Q Luo, Y Li, X Lin, L Fan, Y Zhang, J Liu, Liu, X Liu, Fabrication of Red Blood Cell Based Multi-modal Theranostic Probes for the Second Near-infrared WindowFluorescent Imaging-guided Tumor Surgery and Photodynamic Therapy, Theranostics, 2019, 9(2): 369-380；