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雍建平

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姓名

雍建平 

性别

职务

-

职称

副研究员

地址

福建省厦门市集美区兑山西珩路258号

邮编

jpyongfjirsm.ac.cn

邮箱

361021

 

    简历:

 

    雍建平,博士,副研究员

 
    2014年底加入中科院海西研究院厦门稀土材料研究所。近年来作为 第一作者或通讯作者在Letters in Organic Chemistry; Medicinal Chemistry; Anticancer agents Med. Chem.; Curr. Pharm. Des.; Med. Chem. Commun.; Chem. Nat. Compd.; Mini-Reviews in Medical Chemistry等相关药化核心杂志发表多篇研究论文;申请及授权多项专利(其中包括2件PCT及2件美国专利)。

 

    研究领域:

 

    1.小分子药物化合物库的设计合成。 

    2.亚热带天然药物的提取分离。 

    3. 电化学探针在中药有效成分中的定性定量分析。

 

    代表论著:

 
    1. Jianping Yong, xueming Yang, Can-zhong Lu*, Xiaoyuan Wu. Synthesis of 1,1’-Ferrocene Diformates Bearing Isoxazole Moiety and Preliminarily Cytotoxicity to A549, HCT116 and MCF-7 Cell Lines. Letters in Drug Design & Discovery. 2018,15(11):1141-1146(封面文章)

 
    2. Jianping Yong, Can-zhong Lu*, xiaoyuan Wu. Synthesis and Preliminarily Cytotoxicity to A549, HCT116 and MCF-7 Cell Lines of Thieno[2,3-d]pyrimidine Derivatives containing Isoxazole Moiety. Letters in Drug Design & Discovery. 2018,15(5):463-474. (封面文章)

 
    3. Jianping Yong, Can-zhong Lu*, xiaoyuan Wu. Synthesis of metronidazole derivatives and their in vitro anticancer activity. Letters in Organic Chemistry. 2016, 13(4):283-288

 
    4. Jianping Yong, Can-zhong Lu*, xiaoyuan Wu. Synthesis, structural characterization of a novel ferrocene derivative and preliminarily anticancer activity. Medicinal Chemistry. 2016, 12(5), 426-431

 
    5. Jianping Yong, Canzhong Lu*, Xiaoyuan Wu. Synthesis of isoxazole moiety containing thieno[2,3-d]-yrimidine derivatives and preliminarily in vitro anticancer activity (Part II). Anticancer agents Med. Chem. 2015, 15(9):1148-1155.

 
    6. Jianping Yong, Canzhong Lu*, Xiaoyuan Wu. Synthesis and biological evaluation of quinazoline derivatives as potential anticancer agents (II). Anticancer agents Med. Chem. 2015, 15(10): 1326-1332.

 
    7. Jianping Yong , Canzhong Lu*, Xiaoyuan Wu. Potential anticancer agents I. synthesis of isoxazole moiety containing quinazoline derivatives and preliminarily in vitro anticancer activity. Anticancer agents Med. Chem. 2015, 15(1): 131-136.(封面文章)。 This paper was selected to be featured in the World Biomedical Frontiers [ISSN:2328-0166], for its innovation and potential for significant impact.

 
    8. Jianping Yong, Canzhong Lu*, Xiaoyuan Wu. Anticancer Advances of Matrine and Its Derivatives. Curr. Pharm. Des. 2015, 21(25): 3673-3680.

 
    9. Jianping Yong, Can-zhong Lu*, xiaoyuan Wu. Synthesis of Isoxazole Moiety Containing Ferrocene Derivatives and Preliminarily in vitro Anticancer Activity. Med. Chem. Comm. 2014,5(7):968-972

 
    10. Jianping Yong, xiaoyuan Wu, Can-zhong Lu*, Chemical constitutes isolated from the fruits of Lonicera maackii (Rupr.) Maxim. Chem. Nat. Compd. 2014. 50(4): 765-766

 
    11.Jianping Yong, Can-zhong Lu*, Shuijing Huang, Chemical constitutes isolated from the flower and fruits of Lonicera maackii (Rupr.) Maxim. Chem. Nat. Compd. 2014. 50(5):945-947.

 
    12. Jianping Yong, Can-zhong Lu*, et al , Chemical components isolated from the roots of Morinda officinalis How. Chem. Nat. Compd. 2015, 50(3):548-549. 


    13. Jianping Yong, Can-zhong Lu, Haji Akber Aisa*. Advances in Studies on the Rupestonic Acid Derivatives as Anti-influenza Agents. Mini-Reviews in Medical Chemistry. 2013, 13(2): 310-315. 
 

    申请及授权专利:

 
    1. Canzhong Lu, Jianping Yong, Quinazoline derivatives and application thereof. PCT/WO2013143319A1; U. S. patent: 9193718B2 (2015年11月24日授权);EP 2752413B1(2016年3月23日授权);ZL201210526123.X (2016年4月27日授权)

 
    2. Canzhong Lu, Jianping Yong. Thieno[2,3-d]Pyrimidine derivatives, preparation method and use Thereof. PCT/WO2014043866A1;U. S patent: 9434741B2 (2016年9月6日授权); EP 2835372B1(2016年5月4日授权); ZL201210349508.3 (2016年12月28日授权) 


    3. Yong, Jianping, Lu, Canzhong. Ferrocene drivatives, preparation method and use thereof. U. S. patent: 9738673B1 (2017年8月22日授权).

 

    4.雍建平.卢灿忠, 喹啉衍生物、其制备方法及其用途. ZL201410445335.4(2017年6月6日授权)

 
    5. 雍建平.卢灿忠, 含氮氧自由基二茂铁衍生物的制备方法及用途. ZL201510147804.9 (2017年8月15日授权)

 
    6. 雍建平,卢灿忠, 二茂铁衍生物、其制备方法及用途. ZL201310239745.9 (2018年5月11日授权)

 
    7. 雍建平,卢灿忠, 二茂铁衍生物、制备方法及其用途. ZL201310608170.3(2018年9月28日授权)

 
    8. 雍建平.卢灿忠, 甲硝唑衍生物的制备方法及用途. ZL201510396700.1(2018年10月2日授权)

 
    9. 雍建平.卢灿忠, 喹唑啉衍生物的制备方法及用途. ZL201410067346.3(2019年3月8日授权)

 
    10. Canzhong Lu, Jianping Yong, Quinazoline derivatives and application thereof. PCT/WO2013143319A1; 中国专利公开号:CN 103360382 A

 
    11. Yong, Jianping, Lu, Canzhong. Nicotinic acid derivatives, their prepareation and the use thereof . U. S. patent: 15/816,723

 
    12. 雍建平,卢灿忠, 二茂铁甲醚的制备方法及其用途.公开号:CN103588823A

 
    13. 雍建平.卢灿忠, 一类可降解药物载体材料的制备及用途. 公开号:CN103804418A

 
    14.雍建平.卢灿忠, 二茂铁衍生物及其制备方法和用途. 公开号:CN106518933A 


    15. 雍建平.卢灿忠, 二茂铁甲酸衍生物、其制备方法和用途. 公开号:CN 106905379 A

 
    16. 雍建平.卢灿忠. 吡啶-2-甲酸衍生物及其制备方法与用途. 公开号:CN 110066274A

 
    17. 雍建平.卢灿忠. 异烟酸衍生物及其制备方法和用途. 公开号:CN 109942566 A

 
    18. 雍建平.卢灿忠, 张世碧. 一种竹柏籽油的制备方法及用途. 申请号:201910219308.8(2019年3月22日受理) 

 

 

 

 
中国科学院海西研究院厦门稀土材料研究所
地址:福建省厦门市集美区兑山西珩路258号   邮政编码:361021
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